A paper by Professor Keiji Itaka and colleagues on myocardial repair following myocardial infarction, part of Research and Development Project 2, has been published in *Small Science*.
As the population continues to age, the number of patients with chronic heart failure—often referred to as “cardiac frailty”—is on the rise. Amid predictions of a heart failure pandemic by 2030, a team led by Keishi Iitaka, Principal Investigator of iCONM (Professor at Osaka University) under Research and Development Project 2, identified five factors that restore cardiac function in mice with ischemic damage. They discovered that delivering the mRNA for these factors to the myocardium via nanomicelles improves cardiac function. These findings were published in the academic journal *Small Science* and have been widely reported by media outlets both in Japan and abroad.
Please see below for details:
https://change.kawasaki-net.ne.jp/en/project/performance/1215
