Concrete Research Activities
(Research Themes)

Leader: Graduate School of Engineering,
The University of Tokyo

Prof. Ken Uchida

Currently, many tests, including blood tests, cannot be performed without a visit to a medical institution. Our team is investigating downsizing and non-invasive methods, such as biochemical tests instead of blood sampling, to enable these tests to be performed at home whenever possible. We plan to develop a system where a breath sensor installed in the living room can monitor daily health conditions while the patient goes about their normal daily activities at home.

Leader: Laboratory for Biomaterials and Bioengineering,
Institute of Science Tokyo

Prof. Akira Matsumoto

While managing medication compliance according to the patient's conditions is important in clinical pharmacy, it is not easy to achieve this at home. Our team aims to optimize medication management at home by developing an attachable drug concentration management device that measures specific biomarkers in body fluids and automatically administers drugs at appropriate doses based on those values. We will also develop a biopharmaceutical formulation that can be administered via inhalation or a skin patch, allowing it to be used for home medical care without the need to visit medical institutions.

Leader: Laboratory for Chemistry and Life Science,
Institute of Science Tokyo

Prof. Nobuyuki Nishiyama

Research on the signs of aging has been actively conducted in recent years, and their mechanisms are gradually being elucidated. Based on these findings, our team will develop diagnostic methods for the early detection of these signs in the body. We are also working to develop therapeutic technologies and vaccines targeting senescent cells that have accumulated in the body to delay the progression of aging and prevent the onset of age-related diseases, thereby extending healthy life expectancy.

Leader: Frontier Clinical Nursing, Graduate School of Nursing,
Chiba University

Prof. Ayumi Igarashi

To implement newly developed medical technologies in society, it is essential for medical and nursing care professionals, as well as the general public, to understand the perspectives of those who will utilize the technologies. In this team, we aim to develop learning tools and systems for acquiring the basic knowledge and skills necessary to support one's own and others' health (i.e., care competency), which will serve as the foundation for such learning and promote their dissemination and implementation in collaboration with the Research Promotion Organization of Project CHANGE. We are also working to establish a venue for demonstrating and implementing the medical technologies developed in Project CHANGE in the real world.

Leader: Department of Technology and Innovation Management,
Institute of Science Tokyo

Prof. Shintaro Sengoku

Even when groundbreaking technologies and products are developed, they often fail to conform to institutional systems and the future society. For the results of this program's research and development to be smoothly implemented in society, it is necessary to align with systems and regulations that address such challenges, to address ethical, legal, and social issues while practicing responsible research and innovation. In this team, we will take a holistic view of the entire program from a humanities and social science perspective and collaborate with the National Institute of Health Sciences, which is responsible for testing, research, and surveys to properly evaluate safety and efficacy, as well as with domestic and international companies responsible for developing innovative products.