Type Of Media：バイオ工学系専門誌
Publication/Magazine/Media：日経バイオテク
University of Tokyo and iCONM developed nanomedicine that suppresses cancer metastasis by accumulating antisense nucleic acids in lymph nodes.
On July 4, Nikkei Biotech Online published an article about a nanomachine that delivers nucleic acid drugs to sentinel lymph nodes, which was jointly developed by a research team led by Professor Kanjiro Miyata of the University of Tokyo Graduate School of Engineering and the iCONM Kataoka-Kinao Laboratory. Sentinel lymph nodes play an important role as a barrier to breast cancer metastasis, but it is known that the protection of the barrier weakens with advanced cancer. The subject of this study is a paper published in the June 20 J. Am. Chem. Soc. in which a mouse model of triple negative breast cancer, an incurable form of cancer, was used to deliver a nucleic acid medicine that enhances sentinel lymph node defense and suppresses metastasis and recurrence.
https://bio.nikkeibp.co.jp/atcl/news/p1/25/06/30/13476/
https://www.t.u-tokyo.ac.jp/en/press/pr2025-06-24-001
